About The Medical Condition EIF-2alpha Kinase, Heme-Regulated
Find the definition of the medical term EIF-2alpha Kinase, Heme-Regulated. EIF-2alpha Kinase, Heme-Regulated defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
EIF-2alpha Kinase, Heme-Regulated
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What's The Definition Of The Medical Condition EIF-2alpha Kinase, Heme-Regulated?
A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, eiF-2 kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of eIF-2, leading to the inhibition of protein synthesis. EC 2.7.10.-
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