About The Medical Condition Encephalopathies, Hyperbilirubinemic
Find the definition of the medical term Encephalopathies, Hyperbilirubinemic. Encephalopathies, Hyperbilirubinemic defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Encephalopathies, Hyperbilirubinemic
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What's The Definition Of The Medical Condition Encephalopathies, Hyperbilirubinemic?
A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
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