About The Medical Condition ErbB1 Genes
Find the definition of the medical term ErbB1 Genes. ErbB1 Genes defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
ErbB1 Genes
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What's The Definition Of The Medical Condition ErbB1 Genes?
The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.
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