About The Medical Condition Etching, Freeze
Find the definition of the medical term Etching, Freeze. Etching, Freeze defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Etching, Freeze
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What's The Definition Of The Medical Condition Etching, Freeze?
A replica technique in which cells are frozen to a very low temperature and cracked with a knife blade to expose the interior surfaces of the cells or cell membranes. The cracked cell surfaces are then freeze-dried to expose their constituents. The surfaces are now ready for shadowing to be viewed using an electron microscope. This method differs from freeze-fracturing in that no cryoprotectant is used and, thus, allows for the sublimation of water during the freeze-drying process to etch the surfaces.
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