About The Medical Condition Exostosis, Familial

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Exostosis, Familial

Exostosis, Familial Medical Condition Defined & Explained
Exostosis, Familial Medical Condition

What's The Definition Of The Medical Condition Exostosis, Familial?

Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.

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