About The Medical Condition Experimental Autoimmune Myasthenia Gravis, Passive Transfer
Find the definition of the medical term Experimental Autoimmune Myasthenia Gravis, Passive Transfer. Experimental Autoimmune Myasthenia Gravis, Passive Transfer defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Experimental Autoimmune Myasthenia Gravis, Passive Transfer
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What's The Definition Of The Medical Condition Experimental Autoimmune Myasthenia Gravis, Passive Transfer?
Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)
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