About The Medical Condition Extra-Mammary Pagets Disease

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Find the definition of the medical term Extra-Mammary Pagets Disease. Extra-Mammary Pagets Disease defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Extra-Mammary Pagets Disease

Extra-Mammary Pagets Disease Medical Condition Defined & Explained
Extra-Mammary Pagets Disease Medical Condition

What's The Definition Of The Medical Condition Extra-Mammary Pagets Disease?

A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)

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