About The Medical Condition Factor, C3 Nephritic
Find the definition of the medical term Factor, C3 Nephritic. Factor, C3 Nephritic defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Factor, C3 Nephritic
| Factor, C3 Nephritic Medical Condition |
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What's The Definition Of The Medical Condition Factor, C3 Nephritic?
A magnesium-dependent IMMUNOGLOBULIN G autoantibody found in serum of patients with chronic mesangioproliferative hypocomplementemic glomerulonephritis. It causes inactivation of C3 in the alternate pathway by cleaving C3 into two inactive fragments, C3c and C3d, instead of the normal C3b.
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