About The Medical Condition Factor VIII, Thrombin-Activated
Find the definition of the medical term Factor VIII, Thrombin-Activated. Factor VIII, Thrombin-Activated defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Factor VIII, Thrombin-Activated
| Factor VIII, Thrombin-Activated Medical Condition |
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What's The Definition Of The Medical Condition Factor VIII, Thrombin-Activated?
Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similiar in structure and generation to factor Va.
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