About The Medical Condition Factor VIIIa

Find the definition of the medical term Factor VIIIa. Factor VIIIa defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Factor VIIIa

Factor VIIIa Medical Condition |
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What's The Definition Of The Medical Condition Factor VIIIa?
Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similiar in structure and generation to factor Va.
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