About The Medical Condition Familial Exostoses
Find the definition of the medical term Familial Exostoses. Familial Exostoses defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Familial Exostoses
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What's The Definition Of The Medical Condition Familial Exostoses?
Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.
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