About The Medical Condition Fusion Proteins, bcr-abl
Find the definition of the medical term Fusion Proteins, bcr-abl. Fusion Proteins, bcr-abl defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Fusion Proteins, bcr-abl
| Fusion Proteins, bcr-abl Medical Condition |
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What's The Definition Of The Medical Condition Fusion Proteins, bcr-abl?
Translation products of a fusion mRNA derived from the breakpoint cluster region (bcr) gene and a cellular abl (c-abl) gene translocated to chromosome 22. The p210(bcr-abl) fusion protein is found in patients with chronic myelogenous leukemia. The p190(bcr-abl) fusion protein is found in patients with acute lymphocytic leukemia. The activation of human c-abl by chromosomal translocation is essentially the same as the activation of murine c-abl by viral translocation in Abelson murine leukemia virus.
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