About The Medical Condition Futile Substrate Cycle
Find the definition of the medical term Futile Substrate Cycle. Futile Substrate Cycle defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Futile Substrate Cycle
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What's The Definition Of The Medical Condition Futile Substrate Cycle?
A set of opposing, nonequilibrium reactions catalyzed by different enzymes which act simultaneously, with at least one of the reactions driven by ATP hydrolysis. The results of the cycle are that ATP energy is depleted, heat is produced and no net substrate-to-product conversion is achieved. Examples of substrate cycling are cycling of gluconeogenesis and glycolysis pathways and cycling of the triglycerides and fatty acid pathways. Rates of substrate cycling may be increased many-fold in association with hypermetabolic states resulting from severe burns, cold exposure, hyperthyroidism, or acute exercise.
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