About The Medical Condition Gamma-Glutamyltransferases, Protein-Glutamine
Find the definition of the medical term Gamma-Glutamyltransferases, Protein-Glutamine. Gamma-Glutamyltransferases, Protein-Glutamine defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Gamma-Glutamyltransferases, Protein-Glutamine
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What's The Definition Of The Medical Condition Gamma-Glutamyltransferases, Protein-Glutamine?
Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.
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