About The Medical Condition Gangliosidosis G(M2), Type II
Find the definition of the medical term Gangliosidosis G(M2), Type II. Gangliosidosis G(M2), Type II defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Gangliosidosis G(M2), Type II
| Gangliosidosis G(M2), Type II Medical Condition |
|---|
What's The Definition Of The Medical Condition Gangliosidosis G(M2), Type II?
An autosomal inherited disease caused by deficiency of the enzymes hexosaminidase A & B (see BETA-N-ACETYLHEXOSAMINIDASE) which leads to an accumulation of GM2 ganglioside and the sphingolipid globoside in neurons and other organs. Clinical manifestations resemble TAY-SACHS DISEASE, but the disease is not limited to Askenazi Jews and may feature hepatosplenomegaly. The infantile form presents in the first 4 months of life with psychomotor delay, hypotonia followed by spasticity, and cherry red spots in the macula. Rare juvenile and adult forms have been reported. (From Menkes, Textbook of Child Neurology, 5th ed, p92)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Fats, Artificial ‐ Compounds used in food or in food preparation to replace dietary…
- Pupil, Neuropathic Tonic ‐ A pupillary abnormality characterized by a poor pupillary light…
- Feline Coronavirus ‐ A species of CORONAVIRUS infecting cats of all ages and commonly…
- Antigens, CD18 ‐ Cell-surface glycoprotein beta-chains that are non-covalently…
- Pseudoneurotic Schizophrenias ‐ A personality disorder in which there are oddities of thought…
- Infratentorial Neoplasms ‐ Intracranial tumors originating in the region of the brain inferior…
- Dressing, Amniotic Membrane ‐ Human or animal tissue used as temporary wound…
- Pellets, Drug ‐ Small containers or pellets of a solid drug implanted in the…
- Workmans Compensation ‐ Insurance coverage providing compensation and medical benefits…
- Dichloromethyl Ether ‐ A substance that is an irritant to the eyes and respiratory tract…