About The Medical Condition Gene, MDR1
Find the definition of the medical term Gene, MDR1. Gene, MDR1 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Gene, MDR1
| Gene, MDR1 Medical Condition |
|---|
What's The Definition Of The Medical Condition Gene, MDR1?
Genes responsible for multidrug resistance resulting from their overexpression in mammalian cells. Mammalian P-glycoproteins are encoded by small MDR gene familes. The human multidrug resistance 1; (MDR1); gene responds to environmental stress including various anticancer agents. It is a major determinant in the development of resistance to a large number of cancer chemotherapeutic agents. (Biochem Biophys Res Commun 1994;199(3):1428-35; Cancer Res 1994:54(6):1536-41)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Phosphatidyl Inositol Phosphates ‐ Phosphatidylinositols in which one or more alcohol group of the…
- Vesicle, Secretory ‐ Vesicles derived from the GOLGI APPARATUS containing material…
- Beta Keto Acyl Synthetase ‐ An enzyme of long-chain fatty acid synthesis, that adds a two-carbon…
- Pointe, Torsade de ‐ A ventricular tachycardia characterized by periodic twisting…
- Folvite ‐ A member of the vitamin B family that stimulates the hematopoietic…
- Glycogenosis Type II ‐ An autosomal recessively inherited glycogen storage disease caused…
- Endometrial Neoplasm ‐ Tumors or cancer of the inner mucous membrane of…
- Banks, Milk ‐ Centers for acquiring, storing, and distributing…
- Mycobacillin ‐ A cyclic polypeptide antibiotic isolated from culture filtrates…
- Amino Acid Sequence Databases ‐ DATABASES containing information about PROTEINS such as AMINO…