About The Medical Condition Generalized Myasthenia Gravis
Find the definition of the medical term Generalized Myasthenia Gravis. Generalized Myasthenia Gravis defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Generalized Myasthenia Gravis
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What's The Definition Of The Medical Condition Generalized Myasthenia Gravis?
A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)
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