About The Medical Condition Genes, c-myb

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Genes, c-myb

Genes, c-myb Medical Condition Defined & Explained
Genes, c-myb Medical Condition

What's The Definition Of The Medical Condition Genes, c-myb?

Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).

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