About The Medical Condition Genes, MDR
Find the definition of the medical term Genes, MDR. Genes, MDR defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Genes, MDR
| Genes, MDR Medical Condition |
|---|
What's The Definition Of The Medical Condition Genes, MDR?
Genes responsible for multidrug resistance resulting from their overexpression in mammalian cells. Mammalian P-glycoproteins are encoded by small MDR gene familes. The human multidrug resistance 1; (MDR1); gene responds to environmental stress including various anticancer agents. It is a major determinant in the development of resistance to a large number of cancer chemotherapeutic agents. (Biochem Biophys Res Commun 1994;199(3):1428-35; Cancer Res 1994:54(6):1536-41)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Neoplasms, Intracranial ‐ Neoplasms of the intracranial components of the central nervous…
- Aujeszky Disease Virus ‐ A species of VARICELLOVIRUS producing a respiratory infection…
- Syndrome, Marchiafava-Micheli ‐ Disorder characterized by intravascular hemolysis and hemoglobinuria.…
- Hydrochloride, Methamphetamine ‐ A central nervous system stimulant and sympathomimetic with actions…
- Tumor, Medullary ‐ Benign and malignant intra-axial tumors of the MESENCEPHALON;…
- Massages, Heart ‐ Rhythmic compression of the heart by pressure applied manually…
- Proximal Renal Tubular Dysfunction ‐ Constellation of clinical and laboratory manifestations produced…
- Bite Force ‐ The force applied by the masticatory muscles in dental…
- HMSN Type IIs ‐ A hereditary motor and sensory neuropathy transmitted most often…
- Drug Recall ‐ Control of drug and narcotic use by international agreement,…