About The Medical Condition Glycerate 2,3-Bisphosphate

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Find the definition of the medical term Glycerate 2,3-Bisphosphate. Glycerate 2,3-Bisphosphate defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Glycerate 2,3-Bisphosphate

Glycerate 2,3-Bisphosphate Medical Condition Defined & Explained
Glycerate 2,3-Bisphosphate Medical Condition

What's The Definition Of The Medical Condition Glycerate 2,3-Bisphosphate?

A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)

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