About The Medical Condition Gonadal Dysgenesis, 45,X
Find the definition of the medical term Gonadal Dysgenesis, 45,X. Gonadal Dysgenesis, 45,X defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Gonadal Dysgenesis, 45,X
| Gonadal Dysgenesis, 45,X Medical Condition |
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What's The Definition Of The Medical Condition Gonadal Dysgenesis, 45,X?
A syndrome of defective gonadal development in phenotypic women with a karyotype of sex chromosome monosomy (45,X or 45,XO), associated with the loss of a sex chromosome X or Y. Patients generally are of short stature with undifferentiated (streak) gonads, sexual infantilism (HYPOGONADISM), webbing of the neck, cubitus valgus, elevated GONADOTROPINS (LH and FOLLICLE STIMULATING HORMONE) and decreased estradiol level in blood. Studies of Turner Syndrome and its variants have contributed significantly to the understanding of SEX DIFFERENTIATION.
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