About The Medical Condition GTP Cyclohydrolase
Find the definition of the medical term GTP Cyclohydrolase. GTP Cyclohydrolase defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
GTP Cyclohydrolase
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What's The Definition Of The Medical Condition GTP Cyclohydrolase?
(GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II).
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