About The Medical Condition Heme-Regulated eIF-2alpha Kinase
Find the definition of the medical term Heme-Regulated eIF-2alpha Kinase. Heme-Regulated eIF-2alpha Kinase defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Heme-Regulated eIF-2alpha Kinase
| Heme-Regulated eIF-2alpha Kinase Medical Condition |
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What's The Definition Of The Medical Condition Heme-Regulated eIF-2alpha Kinase?
A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, eiF-2 kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of eIF-2, leading to the inhibition of protein synthesis. EC 2.7.10.-
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