About The Medical Condition HSDB-3453
Find the definition of the medical term HSDB-3453. HSDB-3453 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
HSDB-3453
| HSDB-3453 Medical Condition |
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What's The Definition Of The Medical Condition HSDB-3453?
A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.
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