About The Medical Condition Human Class I Antigens
Find the definition of the medical term Human Class I Antigens. Human Class I Antigens defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Human Class I Antigens
| Human Class I Antigens Medical Condition |
|---|
What's The Definition Of The Medical Condition Human Class I Antigens?
Large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin. In humans, three structural genes on chromosome 6 code for the HLA-A; HLA-B and HLA-C antigens. In mice, three genes named K, D, and L on chromosome 17 code for the H-2 antigens. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during graft rejection and restrict cell-mediated lysis of virus-infected cells. They are primarily associated with rheumatologic diseases and certain malignant disorders.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Subacute Sclerosing Panencephalitides ‐ A rare, slowly progressive encephalitis caused by chronic infection…
- Transporter, Erythrocyte Lactate ‐ A family of proteins involved in the transport of monocarboxylic…
- Acid-Specific tRNA, Glutamic ‐ A transfer RNA which is specific for carrying glutamic acid to…
- Transcobalamin I ‐ A group of carrier proteins which bind with vitamin B12 in the…
- Protriptyline ‐ Tricyclic antidepressant similar in action and side effects to…
- Lactic Dehydrogenase Virus ‐ A species ARTERIVIRUS, occurring in a number of transplantable…
- Phages, T7 ‐ Virulent bacteriophage and type species of the genus T7-like…
- Gene Rearrangement ‐ The ordered rearrangement of gene regions by DNA recombination…
- Pain, Shoulder ‐ Unilateral or bilateral pain of the shoulder. It is often caused…
- Technique, Replica ‐ Methods of preparing tissue specimens for visualization using…