About The Medical Condition Huntington Disease, Akinetic-Rigid Variant
Find the definition of the medical term Huntington Disease, Akinetic-Rigid Variant. Huntington Disease, Akinetic-Rigid Variant defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Huntington Disease, Akinetic-Rigid Variant
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What's The Definition Of The Medical Condition Huntington Disease, Akinetic-Rigid Variant?
A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse CHOREA involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
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