About The Medical Condition IGFBP-1

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Find the definition of the medical term IGFBP-1. IGFBP-1 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

IGFBP-1

IGFBP-1 Medical Condition Defined & Explained
IGFBP-1 Medical Condition

What's The Definition Of The Medical Condition IGFBP-1?

One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)

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