About The Medical Condition Immunoglobulin Light-Chain

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Find the definition of the medical term Immunoglobulin Light-Chain. Immunoglobulin Light-Chain defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Immunoglobulin Light-Chain

Immunoglobulin Light-Chain Medical Condition Defined & Explained
Immunoglobulin Light-Chain Medical Condition

What's The Definition Of The Medical Condition Immunoglobulin Light-Chain?

Polypeptide chains, consisting of 211 to 217 amino acid residues, isolated from immunoglobulins and having a molecular weight of approximately 22 kD. There are two major types of light chains, kappa and lambda. In man they are found in a ratio of 60% to 40%, respectively. Both chains consist of linear repeating, similar, but not identical, segments of about 110 amino acid residues. In each segment a disulfide bond establishes a tightly folded approximately 60-membered loop or domain. Adjacent domains are linked by less tightly folded regions. Both light chains contain two such domains. Two light and two heavy chains make one immunoglobulin molecule, but both light chains in one Ig are of the same type.

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