About The Medical Condition Importin-beta

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Find the definition of the medical term Importin-beta. Importin-beta defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Importin-beta

Importin-beta Medical Condition Defined & Explained
Importin-beta Medical Condition

What's The Definition Of The Medical Condition Importin-beta?

Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.

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