About The Medical Condition Inbred CFTR Mouse
Find the definition of the medical term Inbred CFTR Mouse. Inbred CFTR Mouse defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Inbred CFTR Mouse
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What's The Definition Of The Medical Condition Inbred CFTR Mouse?
A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.
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