About The Medical Condition Inhibitor, Collagenase
Find the definition of the medical term Inhibitor, Collagenase. Inhibitor, Collagenase defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Inhibitor, Collagenase
| Inhibitor, Collagenase Medical Condition |
|---|
What's The Definition Of The Medical Condition Inhibitor, Collagenase?
A family of secreted proteins (TIMP-1; TIMP-2; and TIMP-3) that play a crucial role in regulating the activity of the secreted METALLOENDOPEPTIDASES (COLLAGENASES; stromelysins, GELATINASES). Of the three characterized, only TIMP-1 and TIMP-2 appear to have related primary structures and inhibitory properties. They influence the activation of the prometalloproteinase and act to modulate proteolysis of extracellular matrix, notably during tissue remodeling and inflammatory processes. On certain cell types, they can exhibit growth factor-like activity, and they can inhibit the tumorigenic and metastatic phenotype in cancer cells. (Pharmacol Ther 1993;59:329-41)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Adjustment, Case-Mix ‐ The use of severity-of-illness measures, such as age, to estimate…
- Grey Hamster ‐ A genus of the family Muridae consisting of eleven species. C.…
- Synthetic ACTH ‐ A synthetic polypeptide with adrenocorticotropic (CORTICOTROPIN)…
- Puerperal Disorder ‐ Disorders or diseases associated with the six-to-eight-week period…
- Encephalomyelitis Virus, Eastern Equine ‐ A species of ALPHAVIRUS causing encephalomyelitis in Equidae…
- Cell, HT29 ‐ Human colonic adenocarcinoma cells that are able to express differentiation…
- Aqueous Humor Shunt ‐ Devices, usually incorporating unidirectional valves, which are…
- Therapy, Language ‐ Rehabilitation of persons with language disorders or training…
- Osteomalacias ‐ A condition marked by softening of the bones (due to impaired…
- Glucosephosphate Isomerase ‐ An enzyme that catalyzes the reversible interconversion of glucose…