About The Medical Condition Insertional Activation
Find the definition of the medical term Insertional Activation. Insertional Activation defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Insertional Activation
| Insertional Activation Medical Condition |
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What's The Definition Of The Medical Condition Insertional Activation?
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA can be inserted into or adjacent to a cellular proto-oncogene. Insertion of the provirus can cause mutations by interrupting coding sequences or regulatory elements, or cause unregulated expression of the proto-oncogene resulting in tumor formation.
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