About The Medical Condition Insulin Receptor alpha Chain
Find the definition of the medical term Insulin Receptor alpha Chain. Insulin Receptor alpha Chain defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Insulin Receptor alpha Chain
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What's The Definition Of The Medical Condition Insulin Receptor alpha Chain?
A cell surface receptor for INSULIN. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The receptor contains an intrinsic tyrosine kinase domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the LIVER; MUSCLE; and ADIPOSE TISSUE. EC 2.7.11.-.
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