About The Medical Condition Isocitrate Dehydrogenase-I
Find the definition of the medical term Isocitrate Dehydrogenase-I. Isocitrate Dehydrogenase-I defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Isocitrate Dehydrogenase-I
| Isocitrate Dehydrogenase-I Medical Condition |
|---|
What's The Definition Of The Medical Condition Isocitrate Dehydrogenase-I?
An enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+, Mn2+; it is activated by ADP, citrate, and Ca2+, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (From Dorland, 27th ed) (The NADP+ enzyme is EC 1.1.1.42.) EC 1.1.1.41.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Proteins, Encephalitogenic Basic ‐ A group of 7 proteins produced from a single gene by alternate…
- Dicarboxylate Carrier ‐ A family of ORGANIC ION TRANSPORTERS that specifically transport…
- Brainstem Neoplasms, Primary ‐ Benign and malignant intra-axial tumors of the MESENCEPHALON;…
- Long-Term Care Insurance ‐ Health insurance to provide full or partial coverage for long-term…
- Unilateral Headache ‐ Pain in the cranial region that may occur as an isolated and…
- Postoperative Pains ‐ Pain during the period…
- Platelet Transforming Growth Factor ‐ A factor synthesized in a wide variety of tissues. It acts synergistically…
- Frontal Gait ‐ Gait abnormalities that are a manifestation of nervous system…
- Compression, Spinal Cord ‐ Acute and chronic conditions characterized by external mechanical…
- Disturbances, Menstruation ‐ Variations of menstruation which may be indicative…