About The Medical Condition Isotype Switching

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Find the definition of the medical term Isotype Switching. Isotype Switching defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Isotype Switching

Isotype Switching Medical Condition Defined & Explained
Isotype Switching Medical Condition

What's The Definition Of The Medical Condition Isotype Switching?

Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.

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