About The Medical Condition Isotype Switchings
Find the definition of the medical term Isotype Switchings. Isotype Switchings defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Isotype Switchings
| Isotype Switchings Medical Condition |
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What's The Definition Of The Medical Condition Isotype Switchings?
Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.
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