About The Medical Condition Karyopherins, alpha
Find the definition of the medical term Karyopherins, alpha. Karyopherins, alpha defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Karyopherins, alpha
| Karyopherins, alpha Medical Condition |
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What's The Definition Of The Medical Condition Karyopherins, alpha?
Nucleocytoplasmic transport molecules that bind to the NUCLEAR LOCALIZATION SIGNAL of cytoplasmic molecules destined to be imported into the CELL NUCLEUS. Once attached to their cargo they bind to BETA KARYOPHERINS and are transported through the NUCLEAR PORE COMPLEX. Inside the CELL NUCLEUS alpha karyopherins dissociate from beta karypherins and their cargo. They then form a complex with CELLULAR APOPTOSIS SUCCEPTIBILITY PROTEIN and RAN GTP-BINDING PROTEIN which is exported to the CYTOPLASM.
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