About The Medical Condition Kinase 1, Cyclin-Dependent
Find the definition of the medical term Kinase 1, Cyclin-Dependent. Kinase 1, Cyclin-Dependent defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Kinase 1, Cyclin-Dependent
Kinase 1, Cyclin-Dependent Medical Condition |
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What's The Definition Of The Medical Condition Kinase 1, Cyclin-Dependent?
Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the cell cycle. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of p34cdc2 is achieved when it is fully dephosphorylated. Protein p34cdc2, the product of the cdc2 gene in Schizosaccharomyces pombe, should not be confused with the unrelated product of the CDC2 gene in Saccharomyces cerevisiae that forms the large subunit of DNA polymerase III.
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