About The Medical Condition Kinase, eIF-2alpha

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Kinase, eIF-2alpha

Kinase, eIF-2alpha Medical Condition Defined & Explained
Kinase, eIF-2alpha Medical Condition

What's The Definition Of The Medical Condition Kinase, eIF-2alpha?

A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, eiF-2 kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of eIF-2, leading to the inhibition of protein synthesis. EC 2.7.10.-

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