About The Medical Condition Kit Proto-Oncogene Protein
Find the definition of the medical term Kit Proto-Oncogene Protein. Kit Proto-Oncogene Protein defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Kit Proto-Oncogene Protein
| Kit Proto-Oncogene Protein Medical Condition |
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What's The Definition Of The Medical Condition Kit Proto-Oncogene Protein?
A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis. EC 2.7.11.-.
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