About The Medical Condition LEOPARD Syndrome
Find the definition of the medical term LEOPARD Syndrome. LEOPARD Syndrome defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
LEOPARD Syndrome
| LEOPARD Syndrome Medical Condition |
|---|
What's The Definition Of The Medical Condition LEOPARD Syndrome?
An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic neural crest. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- CD140A Antigens ‐ A PDGF receptor that binds specifically to both PDGF-A chains…
- Broadsides [Publication Type] ‐ Separately published pieces of paper or other material, usually…
- Strongyloses, Equine ‐ Infection of horses with parasitic nematodes of the superfamily…
- Mature Teratomas ‐ A true neoplasm composed of a number of different types of tissue,…
- Paraganglioma ‐ A neural crest tumor usually derived from the chromoreceptor…
- Affinity Chromatographies ‐ A chromatographic technique that utilizes the ability of biological…
- Gyno-Pevaril ‐ A broad spectrum antimycotic with some action against Gram positive…
- System, ABO Blood-Group ‐ The major human blood type system which depends on the presence…
- Series, Fourier ‐ Analysis based on the mathematical function first formulated…
- Elements, Anti-Sense ‐ Nucleic acids which hybridize to complementary sequences in other…