About The Medical Condition Lpr Mouse, MRL
Find the definition of the medical term Lpr Mouse, MRL. Lpr Mouse, MRL defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Lpr Mouse, MRL
| Lpr Mouse, MRL Medical Condition |
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What's The Definition Of The Medical Condition Lpr Mouse, MRL?
A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
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