About The Medical Condition Lupus Coagulation Inhibitor
Find the definition of the medical term Lupus Coagulation Inhibitor. Lupus Coagulation Inhibitor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Lupus Coagulation Inhibitor
| Lupus Coagulation Inhibitor Medical Condition |
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What's The Definition Of The Medical Condition Lupus Coagulation Inhibitor?
An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC), ANTIPHOSPHOLIPID SYNDROME, and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.
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