About The Medical Condition MAP Kinases, ERK
Find the definition of the medical term MAP Kinases, ERK. MAP Kinases, ERK defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
MAP Kinases, ERK
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What's The Definition Of The Medical Condition MAP Kinases, ERK?
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES). Families of these mitogen-activated protein kinases (MAPKs) include extracellular signal-regulated kinases (ERKs), stress-activated protein kinases (SAPKs) (also known as c-jun terminal kinases (JNKs)), and p38-mitogen-activated protein kinases. EC 2,7,1.-
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