About The Medical Condition Maturation-Promoting Factor
Find the definition of the medical term Maturation-Promoting Factor. Maturation-Promoting Factor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Maturation-Promoting Factor
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What's The Definition Of The Medical Condition Maturation-Promoting Factor?
Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.
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