About The Medical Condition Membrane Attack Complex

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Find the definition of the medical term Membrane Attack Complex. Membrane Attack Complex defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Membrane Attack Complex

Membrane Attack Complex Medical Condition Defined & Explained
Membrane Attack Complex Medical Condition

What's The Definition Of The Medical Condition Membrane Attack Complex?

The assembly of complement plasma glycoproteins C5b, C6, C7, C8, and polymeric C9 as a group on biological membranes. The complex forms transmembrane channels which displace lipid molecules and other constituents, thus disrupting the phospholipid bilayer of target cells leading to cell lysis by osmotic leakage. The formation of the membrane attack complex is the terminal step in the complement cascade.

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