About The Medical Condition Mixed Gonadal Dysgenesis
Find the definition of the medical term Mixed Gonadal Dysgenesis. Mixed Gonadal Dysgenesis defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Mixed Gonadal Dysgenesis
| Mixed Gonadal Dysgenesis Medical Condition |
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What's The Definition Of The Medical Condition Mixed Gonadal Dysgenesis?
A type of defective gonadal development in patients with a wide spectrum of chomosomal mosaic variants. Their karyotypes are of partial sex chromosome monosomy resulting from an absence or an abnormal second sex chromosome (X or Y). Karyotypes include 45,X/46,XX; 45,X/46,XX/47,XXX; 46,XXp-; 45,X/46,XY; 45,X/47,XYY; 46,XYpi; etc. The spectrum of phenotypes may range from phenotypic female through pseudohermaphrodite to phenotypic male, depending on the ratio in each gonad of 45,X primordial germ cells to those with normal 46,XX or 46,XY constitution.
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