About The Medical Condition Mixed Lymphocyte Reaction
Find the definition of the medical term Mixed Lymphocyte Reaction. Mixed Lymphocyte Reaction defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Mixed Lymphocyte Reaction
| Mixed Lymphocyte Reaction Medical Condition |
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What's The Definition Of The Medical Condition Mixed Lymphocyte Reaction?
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
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