About The Medical Condition MPGN

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Find the definition of the medical term MPGN. MPGN defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

MPGN

MPGN Medical Condition Defined & Explained
MPGN Medical Condition

What's The Definition Of The Medical Condition MPGN?

Chronic glomerulonephritis characterized histologically by proliferation of mesangial cells, increase in the mesangial matrix, and a thickening of the glomerular capillary walls. The wall thickening is sometimes said to be a result of the interposition of mesangial cytoplasm or matrix between the basement membrane and the endothelium of the capillary wall. It is often divided into types I and II, and sometimes III. Pathogenesis is not well understood, but some types are thought to involve the immune system, with the complement system, in particular, being implicated.

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