About The Medical Condition MPTP-Induced Degeneration of the Striatum
Find the definition of the medical term MPTP-Induced Degeneration of the Striatum. MPTP-Induced Degeneration of the Striatum defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
MPTP-Induced Degeneration of the Striatum
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What's The Definition Of The Medical Condition MPTP-Induced Degeneration of the Striatum?
A condition caused by the neurotoxin 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. MPTP causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)
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